Permanent Replacement of the
Gold-Topped 2.5mL
Serum Separator Tube

NOTE: This notification is generic in nature.  This information notice does not necessarily mean that your Covance CLS supply orders contain 2.5mL serum separator tube(s).

Covance Central Laboratory Services would like to inform sites of a permanent tube replacement within our collection kits.

The gold-topped BD brand 2.5mL serum separator tube is being permanently replaced with the red-topped Greiner brand 2.5mL serum separator tube effective 09 November 2015.  Continue reading

We Need to Hear From You!

survey clip artHave you completed the Investigator Site Survey that was sent last Friday?  It only takes about 5 minutes to complete.

The survey was sent to all active sites and asks brief questions around the services Covance Central Laboratory provides.

If you haven’t already, please take a few minutes to complete the investigator site survey that was sent to you.  Your feedback and comments are important to us!

Thanks in advance for your time.


Investigator Site Survey
Coming Soon!

survey clip artLove working with Covance? Have suggestions for improvements?  Save all those thoughts for the upcoming Investigator Site Survey coming soon.  This short survey (only 8 questions) will ask you to provide feedback on a variety of services from kit production to Investigator Training to Site Communications.

The surveys are anonymous and provide you with a quick way to tell us what we are doing well or where we might need to improve.  Remember, the survey is short and should take less than 5 minutes to complete.

Keep an eye out for the survey coming this month. It will be emailed to all Investigator Sites.

What is Hemolysis and
Why is it Important?

red blood cellHemolysis is defined as the alteration, dissolution or destruction of red blood cell membranes in such a manner that hemoglobin is freed into the medium in which the cells are suspended.  Hemolysis can be caused by antibodies, toxins, chemicals or physical stress from dilution, extremes of pressure, or shear forces or temperature during phlebotomy or preparation of serum.  Even time can cause hemolysis, through the exhaustion of available glucose, which is necessary to maintain the fluidity and stability of the cell membranes. Continue reading


dry iceTo ensure consistency across Covance departments, the next day dry ice order deadline has been changed for US sites from 3:45 PM to 3 PM Eastern Standard Time.  This includes web and phone orders.
If the order is placed either online ( or by phone (866-762-6209) BY 3 PM EST the dry ice orders will be available the next day.
Remember there are benefits to ordering dry ice online:  you get immediate confirmation that your order was placed as well as a tracking number.

Global Team Excels
at Tracking Shipments

global shippingOn any given day, more than 7000 shipments of samples and kits travel around the world between investigator sites and a Covance Central Laboratory or to a third party lab. Tracking those shipments and making sure they arrive safely— and for samples, within stability—is the responsibility of Covance’s logistics department.

The employees in this department are located around the world and are dedicated to tracking all shipments including kits and samples. Continue reading

Reference Ranges
Alerts and Flags

Reference ranges are important criteria to evaluating your patient’s laboratory results.  Covance provides reference ranges that are age and gender specific and represent a heterogeneous clinical trials patient population.   Covance uses a series of flags to represent the meaning of a patient’s test results which fall outside of the reference range.

flags and alerts chart 5

If a patient’s value triggers a flag, it will print on the laboratory report.  Your sponsor may request additional flags.  These will also print on the laboratory report.
In order to ensure timely assessment of patient care, regulations require immediate reporting of laboratory values with potentially critical implications for the patient.  For all HP and LP flags, Covance calls the investigator site and requires a live voice to receive these values and read back.  Notification of other flags are determined by the sponsor of the protocol.

US Labor Day Holiday Reminder

labor-day-star-1To ensure specimens will be received at Covance Central Laboratory in Indianapolis within the established
stability period, please note the observance of the US Labor Day Holiday on Monday, September 7.

Sites should avoid sample collections on Saturday, September 5.

Couriers may reserve the right to schedule earlier than usual pick-up times during the holiday.  Please call your local courier to obtain holiday pick-up schedules.

Send frozen specimens on the next available business day.  Specimens with short stabilities (e.g. Lymphocyte subsets, reticulocyte counts, etc.) should not be collected on the days prior to the holiday.

Please consult Covance Investigator Support at (866) 762-6209 if you have any questions regarding the collection or shipping of specimens.

Southern Georgia Caviar

peppersHere’s a quick, easy recipe to make for the end of summer.

1 Red, Yellow and Green Pepper cut up
1 can Black Beans (Rinsed and Drained)
1 can Yellow Corn, drained
1 can Diced Tomatoes
1 Onion – chopped
½ cup sugar
½ cup Apple Cider Vinegar
½ cup Oil

Mix altogether and marinate OVERNIGHT.  Drain off some of the liquid and serve with tortilla chips

You can easily double this recipe for a very big crowd.